Other genetic bleeding disorders

Many proteins are involved in the cascade of the clotting process. Each genetic malformation in a protein can cause a bleeding disorder. But the expression of the disorder is more rare than haemophilia or Von Willebrand. Each disorder has to be treated by its own specific therapy.

This is a list of the most common other hereditary rare bleeding disorders:

• F I = Fibrinogen Deficiencies: afibrinogenemia; hypofibrinogenemia; dysfibrinogenemia; hypodysfibrinogenemia
• F II = Prothrombin Deficiency
• F V = Factor V-deficiency
• F V-VIII = Combined Factor V-VIII deficiency
• F VII = Factor VII deficiency
• F X = Factor X deficiency
• F XI = Factor XI deficiency
• F XIII = Factor XIII deficiency
• Vit K + ... = Combined deficiency of Vitamin K-dependent Clotting Factors (II, VII, IX, X)
• Glanzman Thrombastenia
• Bernard-Soulier

For short introduction see coagulation

Have also a look at the website of Rare Bleeding disorders:www.rbdd.org